Web Reference: Feb 22, 2026 · Oprah Winfrey has been open about her Ozempic usage, but the legendary TV star's face suggests she may have gone a bit too far with the GLP-1 weight loss drug. Mar 9, 2026 · At 72, Oprah Winfrey's legendary career in show business has often centered around an unfair topic: her weight. She once told People she'd been historically "blamed and shamed" for her fluctuating size. Some people think Oprah Winfrey might have sacrificed comfort when she started taking a GLP-1 drug to lose weight, and it shows in in her awkward gait.
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Last Updated: April 6, 2026
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