Web Reference: Mar 21, 2025 · People use St. John's wort to treat depression and symptoms of menopause. Research on St. John's wort use for specific conditions shows how the supplement may affect those conditions: Depression. Many studies have found St. John's wort to be helpful in treating mild to moderate depression. Feb 6, 2026 · St. John's wort has been used in alternative medicine as a likely effective aid in treating mild to moderate depression and related symptoms such as anxiety or insomnia. Nov 3, 2025 · St. John's wort (Hypericum perforatum) is a flowering plant named for its bright yellow flowers that were said to bloom for the first time around St. John the Baptist's birthday. The word "wort" means "plant" in Old English. People have been using St. John's wort for centuries.
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